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BIBM
2008
IEEE
112views Bioinformatics» more  BIBM 2008»
15 years 11 months ago
Predicting Protective Linear B-Cell Epitopes Using Evolutionary Information
Mapping B-cell epitopes plays an important role in vaccine design, immunodiagnostic tests, and antibody production. Because the experimental determination of B-cell epitopes is ti...
Yasser El-Manzalawy, Drena Dobbs, Vasant Honavar
BIBM
2008
IEEE
110views Bioinformatics» more  BIBM 2008»
15 years 11 months ago
Genome Alignments Using MPI-LAGAN
We develop a parallel algorithm for a widely used whole genome alignment method called LAGAN. We use the MPI-based protocol to develop parallel solutions for two phases of the alg...
Ruinan Zhang, Huzefa Rangwala, George Karypis
120
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BIBE
2007
IEEE
125views Bioinformatics» more  BIBE 2007»
15 years 11 months ago
Large-scale Discovery of Regulatory Motifs Involved in Alternative Splicing
Alternative splicing is a highly important process in many eukaryotic organisms, but surprisingly little is known about its regulation. Often, this process involves cis-regulatory ...
Sihui Zhao, Jihye Kim, Steffen Heber
BIBE
2007
IEEE
108views Bioinformatics» more  BIBE 2007»
15 years 11 months ago
On the Design of Oligos for Gene Synthesis
— Methods for reliable synthesis of long genes offer great promise for protein synthesis via expression of synthetic genes, with applications to improved analysis of protein stru...
Chris Thachuk, Anne Condon
BIBE
2007
IEEE
124views Bioinformatics» more  BIBE 2007»
15 years 11 months ago
Finding Cancer-Related Gene Combinations Using a Molecular Evolutionary Algorithm
—High-throughput data such as microarrays make it possible to investigate the molecular-level mechanism of cancer more efficiently. Computational methods boost the microarray ana...
Chan-Hoon Park, Soo-Jin Kim, Sun Kim, Dong-Yeon Ch...