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137
Voted
CSB
2005
IEEE
166views Bioinformatics» more  CSB 2005»
15 years 10 months ago
Automated Validation of Polymerase Chain Reactions Using Amplicon Melting Curves
PCR, the polymerase chain reaction, is a fundamental tool of molecular biology. Quantitative PCR is the goldstandard methodology for determination of DNA copy numbers, quantitatin...
Tobias P. Mann, Richard Humbert, John A. Stamatoya...
WABI
2005
Springer
143views Bioinformatics» more  WABI 2005»
15 years 10 months ago
A Faster Algorithm for Detecting Network Motifs
Motifs in a network are small connected subnetworks that occur in significantly higher frequencies than in random networks. They have recently gathered much attention as a useful ...
Sebastian Wernicke
CSB
2004
IEEE
141views Bioinformatics» more  CSB 2004»
15 years 8 months ago
MinPD: Distance-Based Phylogenetic Analysis and Recombination Detection of Serially-Sampled HIV Quasispecies
A new computational method to study within-host viral evolution is explored to better understand the evolution and pathogenesis of viruses. Traditional phylogenetic tree methods a...
Patricia Buendia, Giri Narasimhan
CSB
2004
IEEE
146views Bioinformatics» more  CSB 2004»
15 years 8 months ago
Automated Protein Classification Using Consensus Decision
We propose a novel technique for automatically generating the SCOP classification of a protein structure with high accuracy. High accuracy is achieved by combining the decisions o...
Tolga Can, Orhan Çamoglu, Ambuj K. Singh, Y...
120
Voted
CSB
2004
IEEE
110views Bioinformatics» more  CSB 2004»
15 years 8 months ago
SPIDER: Software for Protein Identification from Sequence Tags with De Novo Sequencing Error
For the identification of novel proteins using MS/MS, de novo sequencing software computes one or several possible amino acid sequences (called sequence tags) for each MS/MS spect...
Yonghua Han, Bin Ma, Kaizhong Zhang