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BMCBI
2008
14 years 9 months ago
2008
Background: Most gene finders score candidate gene models with state-based methods, typically HMMs, by combining local properties (coding potential, splice donor and acceptor patt...
BMCBI
2008
14 years 9 months ago
2008
Background: There is great interest in probing the temporal and spatial patterns of cytosine methylation states in genomes of a variety of organisms. It is hoped that this will sh...
BMCBI
2008
14 years 9 months ago
2008
Background: At intermediate stages of genome assembly projects, when a number of contigs have been generated and their validity needs to be verified, it is desirable to align thes...
BMCBI
2006
14 years 9 months ago
2006
Background: Proteins that are similar in sequence or structure may perform different functions in nature. In such cases, function cannot be inferred from sequence or structural si...
BMCBI
2006
14 years 9 months ago
2006
Background: The identification of statistically overrepresented sequences in the upstream regions of coregulated genes should theoretically permit the identification of potential ...