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» Graph Transformation in Molecular Biology
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BIOINFORMATICS
2006
101views more  BIOINFORMATICS 2006»
14 years 9 months ago
A lock-and-key model for protein-protein interactions
Motivation: Protein-protein interaction networks are one of the major post-genomic data sources available to molecular biologists. They provide a comprehensive view of the global ...
Julie L. Morrison, Rainer Breitling, Desmond J. Hi...
89
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BMCBI
2006
144views more  BMCBI 2006»
14 years 9 months ago
Development and implementation of an algorithm for detection of protein complexes in large interaction networks
Background: After complete sequencing of a number of genomes the focus has now turned to proteomics. Advanced proteomics technologies such as two-hybrid assay, mass spectrometry e...
Md. Altaf-Ul-Amin, Yoko Shinbo, Kenji Mihara, Ken ...
81
Voted
ICDM
2005
IEEE
165views Data Mining» more  ICDM 2005»
15 years 3 months ago
Orthogonal Neighborhood Preserving Projections
— Orthogonal Neighborhood Preserving Projections (ONPP) is a linear dimensionality reduction technique which attempts to preserve both the intrinsic neighborhood geometry of the ...
Effrosini Kokiopoulou, Yousef Saad
BMCBI
2010
233views more  BMCBI 2010»
14 years 9 months ago
Odefy -- From discrete to continuous models
Background: Phenomenological information about regulatory interactions is frequently available and can be readily converted to Boolean models. Fully quantitative models, on the ot...
Jan Krumsiek, Sebastian Pölsterl, Dominik M. ...
96
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RECOMB
2006
Springer
15 years 9 months ago
A Parameterized Algorithm for Protein Structure Alignment
This paper proposes a parameterized algorithm for aligning two protein structures, in the case where one protein structure is represented by a contact map graph and the other by a ...
Jinbo Xu, Feng Jiao, Bonnie Berger