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BMCBI
2007
152views more  BMCBI 2007»
15 years 2 months ago
A cross-species alignment tool (CAT)
Background: The main two sorts of automatic gene annotation frameworks are ab initio and alignment-based, the latter splitting into two sub-groups. The first group is used for int...
Heng Li, Liang Guan, Tao Liu, Yiran Guo, Wei-Mou Z...
BMCBI
2007
168views more  BMCBI 2007»
15 years 2 months ago
GOSim - an R-package for computation of information theoretic GO similarities between terms and gene products
Background: With the increased availability of high throughput data, such as DNA microarray data, researchers are capable of producing large amounts of biological data. During the...
Holger Fröhlich, Nora Speer, Annemarie Poustk...
BMCBI
2007
105views more  BMCBI 2007»
15 years 2 months ago
Text-derived concept profiles support assessment of DNA microarray data for acute myeloid leukemia and for androgen receptor sti
Background: High-throughput experiments, such as with DNA microarrays, typically result in hundreds of genes potentially relevant to the process under study, rendering the interpr...
Rob Jelier, Guido Jenster, Lambert C. J. Dorssers,...
BMCBI
2008
102views more  BMCBI 2008»
15 years 2 months ago
Ornithine decarboxylase antizyme finder (OAF): Fast and reliable detection of antizymes with frameshifts in mRNAs
Background: Ornithine decarboxylase antizymes are proteins which negatively regulate cellular polyamine levels via their affects on polyamine synthesis and cellular uptake. In vir...
Michaël Bekaert, Ivaylo P. Ivanov, John F. At...
BMCBI
2008
161views more  BMCBI 2008»
15 years 2 months ago
Inferring gene expression dynamics via functional regression analysis
Background: Temporal gene expression profiles characterize the time-dynamics of expression of specific genes and are increasingly collected in current gene expression experiments....
Hans-Georg Müller, Jeng-Min Chiou, Xiaoyan Le...