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BMCBI
2006
200views more  BMCBI 2006»
14 years 9 months ago
Comparison and evaluation of methods for generating differentially expressed gene lists from microarray data
Background: Numerous feature selection methods have been applied to the identification of differentially expressed genes in microarray data. These include simple fold change, clas...
Ian B. Jeffery, Desmond G. Higgins, Aedín C...
ECCC
2006
134views more  ECCC 2006»
14 years 9 months ago
Derandomizing the AW matrix-valued Chernoff bound using pessimistic estimators and applications
Ahlswede and Winter [AW02] introduced a Chernoff bound for matrix-valued random variables, which is a non-trivial generalization of the usual Chernoff bound for real-valued random...
Avi Wigderson, David Xiao
BMCBI
2007
115views more  BMCBI 2007»
14 years 9 months ago
Recognizing protein-protein interfaces with empirical potentials and reduced amino acid alphabets
Background: In structural genomics, an important goal is the detection and classification of protein–protein interactions, given the structures of the interacting partners. We h...
Guillaume Launay, Raul Mendez, Shoshana J. Wodak, ...
BMCBI
2007
151views more  BMCBI 2007»
14 years 9 months ago
Identification of hot regions in protein-protein interactions by sequential pattern mining
Background: Identification of protein interacting sites is an important task in computational molecular biology. As more and more protein sequences are deposited without available...
Chen-Ming Hsu, Chien-Yu Chen, Baw-Jhiune Liu, Chih...
BMCBI
2005
117views more  BMCBI 2005»
14 years 9 months ago
An evaluation of GO annotation retrieval for BioCreAtIvE and GOA
Background: The Gene Ontology Annotation (GOA) database http://www.ebi.ac.uk/GOA aims to provide high-quality supplementary GO annotation to proteins in the UniProt Knowledgebase....
Evelyn Camon, Daniel Barrell, Emily Dimmer, Vivian...