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BMCBI
2007
95views more  BMCBI 2007»
15 years 2 months ago
Haplotype-based score test for linkage in nuclear families
Background: To look for genetic linkage between angiotensin-I converting enzyme(ACE) gene and hypertension in a Korean adolescent cohort, we developed a powerful test using the co...
Chung Mo Nam, Dae Ryong Kang, Jinheum Kim
BMCBI
2005
148views more  BMCBI 2005»
15 years 2 months ago
Nonparametric tests for differential gene expression and interaction effects in multi-factorial microarray experiments
Background: Numerous nonparametric approaches have been proposed in literature to detect differential gene expression in the setting of two user-defined groups. However, there is ...
Xin Gao, Peter X. K. Song
ISSTA
2009
ACM
15 years 9 months ago
Precise pointer reasoning for dynamic test generation
Dynamic test generation consists of executing a program while gathering symbolic constraints on inputs from predicates encountered in branch statements, and of using a constraint ...
Bassem Elkarablieh, Patrice Godefroid, Michael Y. ...
BMCBI
2007
123views more  BMCBI 2007»
15 years 2 months ago
PedGenie: meta genetic association testing in mixed family and case-control designs
Background-: PedGenie software, introduced in 2006, includes genetic association testing of cases and controls that may be independent or related (nuclear families or extended ped...
Karen Curtin, Jathine Wong, Kristina Allen-Brady, ...
BMCBI
2004
124views more  BMCBI 2004»
15 years 2 months ago
Tests for finding complex patterns of differential expression in cancers: towards individualized medicine
Background: Microarray studies in cancer compare expression levels between two or more sample groups on thousands of genes. Data analysis follows a population-level approach (e.g....
James Lyons-Weiler, Satish Patel, Michael J. Becic...