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BMCBI
2006
130views more  BMCBI 2006»
14 years 12 months ago
An accurate and interpretable model for siRNA efficacy prediction
Background: The use of exogenous small interfering RNAs (siRNAs) for gene silencing has quickly become a widespread molecular tool providing a powerful means for gene functional s...
Jean-Philippe Vert, Nicolas Foveau, Christian Laja...
BMCBI
2006
169views more  BMCBI 2006»
14 years 12 months ago
Assessing protein similarity with Gene Ontology and its use in subnuclear localization prediction
Background: The accomplishment of the various genome sequencing projects resulted in accumulation of massive amount of gene sequence information. This calls for a large-scale comp...
Zhengdeng Lei, Yang Dai
EAAI
2006
189views more  EAAI 2006»
14 years 12 months ago
Evolutionary algorithms for VLSI multi-objective netlist partitioning
The problem of partitioning appears in several areas ranging from VLSI, parallel programming, to molecular biology. The interest in finding an optimal partition especially in VLSI ...
Sadiq M. Sait, Aiman H. El-Maleh, Raslan H. Al-Aba...
BMCBI
2007
123views more  BMCBI 2007»
14 years 12 months ago
BIRCH: A user-oriented, locally-customizable, bioinformatics system
Background: Molecular biologists need sophisticated analytical tools which often demand extensive computational resources. While finding, installing, and using these tools can be ...
Brian Fristensky
BMCBI
2007
113views more  BMCBI 2007»
14 years 12 months ago
Statistical power of phylo-HMM for evolutionarily conserved element detection
Background: An important goal of comparative genomics is the identification of functional elements through conservation analysis. Phylo-HMM was recently introduced to detect conse...
Xiaodan Fan, Jun Zhu, Eric E. Schadt, Jun S. Liu