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BMCBI
2011
14 years 6 months ago
Identifying hypermethylated CpG islands using a quantile regression model
Background: DNA methylation has been shown to play an important role in the silencing of tumor suppressor genes in various tumor types. In order to have a system-wide understandin...
Shuying Sun, Zhengyi Chen, Pearlly Yan, Yi-Wen Hua...
IANDC
2011
148views more  IANDC 2011»
14 years 6 months ago
Building species trees from larger parts of phylogenomic databases
Abstract. Gene trees are leaf-labeled trees inferred from molecular sequences. Due to duplication events arising in genome evolution, gene trees usually have multiple copies of som...
Celine Scornavacca, Vincent Berry, Vincent Ranwez
MCM
2011
14 years 6 months ago
Circadian rhythm and cell population growth
Molecular circadian clocks, that are found in all nucleated cells of mammals, are known to dictate rhythms of approximately 24 hours (circa diem) to many physiological processes. ...
Jean Clairambault, Stéphane Gaubert, Thomas...
NAR
2011
307views Computer Vision» more  NAR 2011»
14 years 6 months ago
BRENDA, the enzyme information system in 2011
The BRENDA (BRaunschweig ENzyme Database, http://www.brenda-enzymes.org) enzyme information system is the main collection of enzyme functional and property data for the scientific...
Maurice Scheer, Andreas Grote, Antje Chang, Ida Sc...
JUCS
2010
215views more  JUCS 2010»
14 years 6 months ago
A Multidisciplinary Survey of Computational Techniques for the Modelling, Simulation and Analysis of Biochemical Networks
: All processes of life are controlled by networks of interacting biochemical components. The purpose of modelling these networks is manifold. From a theoretical point of view it a...
James Decraene, Thomas Hinze