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BMCBI
2006
116views more  BMCBI 2006»
14 years 11 months ago
HotSwap for bioinformatics: A STRAP tutorial
Background: Bioinformatics applications are now routinely used to analyze large amounts of data. Application development often requires many cycles of optimization, compiling, and...
Christoph Gille, Peter N. Robinson
COMPUTER
2006
84views more  COMPUTER 2006»
14 years 11 months ago
Testable, Reusable Units of Cognition
The educational content of a technical topic consists, ultimately, of elementary chunks of knowledge. Identifying and classifying such units -- Testable, Reusable Units of Cogniti...
Bertrand Meyer
BMCBI
2007
182views more  BMCBI 2007»
14 years 11 months ago
Identifying regulatory targets of cell cycle transcription factors using gene expression and ChIP-chip data
Background: ChIP-chip data, which indicate binding of transcription factors (TFs) to DNA regions in vivo, are widely used to reconstruct transcriptional regulatory networks. Howev...
Wei-Sheng Wu, Wen-Hsiung Li, Bor-Sen Chen
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BMCBI
2007
115views more  BMCBI 2007»
14 years 11 months ago
Seven Golden Rules for heuristic filtering of molecular formulas obtained by accurate mass spectrometry
Background: Structure elucidation of unknown small molecules by mass spectrometry is a challenge despite advances in instrumentation. The first crucial step is to obtain correct e...
Tobias Kind, Oliver Fiehn
BMCBI
2007
102views more  BMCBI 2007»
14 years 11 months ago
qPIPSA: Relating enzymatic kinetic parameters and interaction fields
Background: The simulation of metabolic networks in quantitative systems biology requires the assignment of enzymatic kinetic parameters. Experimentally determined values are ofte...
Razif R. Gabdoulline, Matthias Stein, Rebecca C. W...