2013 search results - page 313 / 403 » Happy New Year |
BMCBI
2011
14 years 6 months ago
2011
Background: Designing maximally selective ligands that act on individual targets is the dominant paradigm in drug discovery. Poor selectivity can underlie toxicity and side effect...
108
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BMCBI
2011
14 years 6 months ago
2011
Background: Discovery of biomarkers that are correlated with therapy response and thus with survival is an important goal of medical research on severe diseases, e.g. cancer. Freq...
156
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HPCA
2011
IEEE
14 years 3 months ago
2011
IEEE
Over the last twenty years the interfaces for accessing persistent storage within a computer system have remained essentially unchanged. Simply put, seek, read and write have de�...
114
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BMCBI
2011
14 years 3 months ago
2011
Background: With next-generation sequencing technologies, experiments that were considered prohibitive only a few years ago are now possible. However, while these technologies hav...
102
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BMCBI
2011
14 years 3 months ago
2011
Background: Flux coupling analysis (FCA) is a useful method for finding dependencies between fluxes of a metabolic network at steady-state. FCA classifies reactions into subsets (...