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» Hardening Functions for Large Scale Distributed Computations
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BMCBI
2010
156views more  BMCBI 2010»
15 years 4 months ago
Mathematical model for empirically optimizing large scale production of soluble protein domains
Background: Efficient dissection of large proteins into their structural domains is critical for high throughput proteome analysis. So far, no study has focused on mathematically ...
Eisuke Chikayama, Atsushi Kurotani, Takanori Tanak...
BMCBI
2007
265views more  BMCBI 2007»
15 years 4 months ago
Large scale clustering of protein sequences with FORCE -A layout based heuristic for weighted cluster editing
Background: Detecting groups of functionally related proteins from their amino acid sequence alone has been a long-standing challenge in computational genome research. Several clu...
Tobias Wittkop, Jan Baumbach, Francisco P. Lobo, S...
SIGIR
2006
ACM
15 years 10 months ago
Large scale semi-supervised linear SVMs
Large scale learning is often realistic only in a semi-supervised setting where a small set of labeled examples is available together with a large collection of unlabeled data. In...
Vikas Sindhwani, S. Sathiya Keerthi
ISCA
1993
IEEE
112views Hardware» more  ISCA 1993»
15 years 8 months ago
Working Sets, Cache Sizes, and Node Granularity Issues for Large-Scale Multiprocessors
The distribution of resources among processors, memory and caches is a crucial question faced by designers of large-scale parallel machines. If a machine is to solve problems with...
Edward Rothberg, Jaswinder Pal Singh, Anoop Gupta
BMCBI
2007
114views more  BMCBI 2007»
15 years 4 months ago
Large scale statistical inference of signaling pathways from RNAi and microarray data
Background: The advent of RNA interference techniques enables the selective silencing of biologically interesting genes in an efficient way. In combination with DNA microarray tec...
Holger Fröhlich, Mark Fellmann, Holger Sü...