46 search results - page 1 / 10 » Hidden Markov models for detecting remote protein homologies |
BIOINFORMATICS
1998
13 years 6 months ago
1998
JCB
2000
13 years 6 months ago
2000
A new method for detecting remote protein homologies is introduced and shown to perform well in classifying protein domains by SCOP superfamily. The method is a variant of support...
BMCBI
2010
13 years 6 months ago
2010
Background: Profile hidden Markov models (profile-HMMs) are sensitive tools for remote protein homology detection, but the main scoring algorithms, Viterbi or Forward, require con...
RECOMB
2002
Springer
14 years 6 months ago
2002
Springer
One key element in understanding the molecular machinery of the cell is to understand the meaning, or function, of each protein encoded in the genome. A very successful means of i...
JCB
2002
13 years 5 months ago
2002
We describe a new algorithm for protein classi cation and the detection of remote homologs. The rationale is to exploit both vertical and horizontal information of a multiple alig...