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BMCBI
2008
195views more  BMCBI 2008»
15 years 5 months ago
Goldsurfer2 (Gs2): A comprehensive tool for the analysis and visualization of genome wide association studies
Background: Genome wide association (GWA) studies are now being widely undertaken aiming to find the link between genetic variations and common diseases. Ideally, a well-powered G...
Fredrik Pettersson, Andrew P. Morris, Michael R. B...
BMCBI
2008
179views more  BMCBI 2008»
15 years 5 months ago
Bayesian modeling of recombination events in bacterial populations
Background: We consider the discovery of recombinant segments jointly with their origins within multilocus DNA sequences from bacteria representing heterogeneous populations of fa...
Pekka Marttinen, Adam Baldwin, William P. Hanage, ...
BMCBI
2005
98views more  BMCBI 2005»
15 years 4 months ago
InterferenceAnalyzer: Tools for the analysis and simulation of multi-locus genetic data
Background: Good statistical models for analyzing and simulating multilocus recombination data exist but are not accessible to many biologists because their use requires reasonabl...
Lalitha Viswanath, Elizabeth A. Housworth
BMCBI
2011
14 years 8 months ago
Estimation of allele frequency and association mapping using next-generation sequencing data
Background: Estimation of allele frequency is of fundamental importance in population genetic analyses and in association mapping. In most studies using next-generation sequencing...
Su Yeon Kim, Kirk E. Lohmueller, Anders Albrechtse...
EDBT
2012
ACM
247views Database» more  EDBT 2012»
13 years 7 months ago
Heuristics-based query optimisation for SPARQL
Query optimization in RDF Stores is a challenging problem as SPARQL queries typically contain many more joins than equivalent relational plans, and hence lead to a large join orde...
Petros Tsialiamanis, Lefteris Sidirourgos, Irini F...