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BMCBI
2010
101views more  BMCBI 2010»
15 years 11 hour ago
Hidden Markov model speed heuristic and iterative HMM search procedure
Background: Profile hidden Markov models (profile-HMMs) are sensitive tools for remote protein homology detection, but the main scoring algorithms, Viterbi or Forward, require con...
L. Steven Johnson, Sean R. Eddy, Elon Portugaly
BMCBI
2007
130views more  BMCBI 2007»
15 years 11 hour ago
HMM-ModE - Improved classification using profile hidden Markov models by optimising the discrimination threshold and modifying e
Background: Profile Hidden Markov Models (HMM) are statistical representations of protein families derived from patterns of sequence conservation in multiple alignments and have b...
Prashant K. Srivastava, Dhwani K. Desai, Soumyadee...
AIEDU
2005
185views more  AIEDU 2005»
14 years 11 months ago
A Bayesian Student Model without Hidden Nodes and its Comparison with Item Response Theory
The Bayesian framework offers a number of techniques for inferring an individual's knowledge state from evidence of mastery of concepts or skills. A typical application where ...
Michel C. Desmarais, Xiaoming Pu
BMCBI
2010
118views more  BMCBI 2010»
15 years 14 hour ago
Predicting nucleosome positioning using a duration Hidden Markov Model
Background: The nucleosome is the fundamental packing unit of DNAs in eukaryotic cells. Its detailed positioning on the genome is closely related to chromosome functions. Increasi...
Liqun Xi, Yvonne Fondufe-Mittendorf, Lei Xia, Jare...
BMCBI
2006
147views more  BMCBI 2006»
14 years 12 months ago
A hidden Markov model approach for determining expression from genomic tiling micro arrays
Background: Genomic tiling micro arrays have great potential for identifying previously undiscovered coding as well as non-coding transcription. To-date, however, analyses of thes...
Kasper Munch, Paul P. Gardner, Peter Arctander, An...