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BIOSYSTEMS
2008
129views more  BIOSYSTEMS 2008»
15 years 24 days ago
Reconstruction of DNA sequences using genetic algorithms and cellular automata: Towards mutation prediction?
Change of DNA sequence that fuels evolution is, to a certain extent, a deterministic process because mutagenesis does not occur in an absolutely random manner. So far, it has not ...
Ch. Mizas, Georgios Ch. Sirakoulis, Vasilios A. Ma...
BMCBI
2007
237views more  BMCBI 2007»
15 years 24 days ago
FLAME, a novel fuzzy clustering method for the analysis of DNA microarray data
Background: Data clustering analysis has been extensively applied to extract information from gene expression profiles obtained with DNA microarrays. To this aim, existing cluster...
Limin Fu, Enzo Medico
110
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BMCBI
2007
135views more  BMCBI 2007»
15 years 24 days ago
Measuring similarities between gene expression profiles through new data transformations
Background: Clustering methods are widely used on gene expression data to categorize genes with similar expression profiles. Finding an appropriate (dis)similarity measure is crit...
Kyungpil Kim, Shibo Zhang, Keni Jiang, Li Cai, In-...
109
Voted
BMCBI
2008
126views more  BMCBI 2008»
15 years 24 days ago
FCI: an R-based algorithm for evaluating uncertainty of absolute real-time PCR quantification
Background: FCI is an R code for analyzing data from real-time PCR experiments. This algorithm estimates standard curve features as well as nucleic acid concentrations and confide...
Paolo Verderio, Sara Pizzamiglio, Fabio Gallo, Sim...
88
Voted
BMCBI
2007
119views more  BMCBI 2007»
15 years 24 days ago
A dynamic programming approach for the alignment of signal peaks in multiple gas chromatography-mass spectrometry experiments
Background: Gas chromatography-mass spectrometry (GC-MS) is a robust platform for the profiling of certain classes of small molecules in biological samples. When multiple samples ...
Mark D. Robinson, David P. De Souza, Woon Wai Keen...
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