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COMPSAC
2004
IEEE
15 years 3 months ago
Protein Functional Motion Query and Visualization
Function is a dynamic property closely related to the conformational mechanisms of the protein structure in its physiological environment. Efficient methods and tools for predicti...
Xiong Liu, Hassan A. Karimi, Lee-Wei Yang, Ivet Ba...
BMCBI
2010
176views more  BMCBI 2010»
14 years 11 months ago
Bayesian statistical modelling of human protein interaction network incorporating protein disorder information
Background: We present a statistical method of analysis of biological networks based on the exponential random graph model, namely p2-model, as opposed to previous descriptive app...
Svetlana Bulashevska, Alla Bulashevska, Roland Eil...
CSB
2003
IEEE
176views Bioinformatics» more  CSB 2003»
15 years 5 months ago
3D Structural Homology Detection via Unassigned Residual Dipolar Couplings
Recognition of a protein’s fold provides valuable information about its function. While many sequence-based homology prediction methods exist, an important challenge remains: tw...
Christopher James Langmead, Bruce Randall Donald
BMCBI
2004
208views more  BMCBI 2004»
14 years 11 months ago
Using 3D Hidden Markov Models that explicitly represent spatial coordinates to model and compare protein structures
Background: Hidden Markov Models (HMMs) have proven very useful in computational biology for such applications as sequence pattern matching, gene-finding, and structure prediction...
Vadim Alexandrov, Mark Gerstein
91
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NAR
2006
98views more  NAR 2006»
14 years 11 months ago
oGNM: online computation of structural dynamics using the Gaussian Network Model
An assessment of the equilibrium dynamics of biomolecular systems, and in particular their most cooperativefluctuationsaccessibleundernativestate conditions, is a first step towar...
Lee-Wei Yang, A. J. Rader, Xiong Liu, Christopher ...