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BMCBI
2010
156views more  BMCBI 2010»
14 years 9 months ago
Protein complex prediction via verifying and reconstructing the topology of domain-domain interactions
Background: High-throughput methods for detecting protein-protein interactions enable us to obtain large interaction networks, and also allow us to computationally identify the as...
Yosuke Ozawa, Rintaro Saito, Shigeo Fujimori, Hisa...
BMCBI
2010
167views more  BMCBI 2010»
14 years 9 months ago
Creating PWMs of transcription factors using 3D structure-based computation of protein-DNA free binding energies
Background: Knowledge of transcription factor-DNA binding patterns is crucial for understanding gene transcription. Numerous DNA-binding proteins are annotated as transcription fa...
Denitsa Alamanova, Philip Stegmaier, Alexander E. ...
JCC
2010
105views more  JCC 2010»
14 years 8 months ago
Fast determination of the optimal rotational matrix for macromolecular superpositions
: Finding the rotational matrix that minimizes the sum of squared deviations between two vectors is an important problem in bioinformatics and crystallography. Traditional algorith...
Pu Liu, Dimitris K. Agrafiotis, Douglas L. Theobal...
BMCBI
2010
208views more  BMCBI 2010»
14 years 9 months ago
Calculation of accurate small angle X-ray scattering curves from coarse-grained protein models
Background: Genome sequencing projects have expanded the gap between the amount of known protein sequences and structures. The limitations of current high resolution structure det...
Kasper Stovgaard, Christian Andreetta, Jesper Ferk...
NAR
2011
252views Computer Vision» more  NAR 2011»
14 years 14 days ago
BISC: Binary SubComplexes in proteins database
Binary subcomplexes in proteins database (BISC) is a new protein–protein interaction (PPI) database linking up the two communities most active in their characterization: structu...
Thomas Juettemann, Dietlind L. Gerloff