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102
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BMCBI
2007
183views more  BMCBI 2007»
15 years 28 days ago
Considerations in the identification of functional RNA structural elements in genomic alignments
Background: Accurate identification of novel, functional noncoding (nc) RNA features in genome sequence has proven more difficult than for exons. Current algorithms identify and s...
Tomas Babak, Benjamin J. Blencowe, Timothy R. Hugh...
90
Voted
BMCBI
2007
126views more  BMCBI 2007»
15 years 28 days ago
Including probe-level uncertainty in model-based gene expression clustering
Background: Clustering is an important analysis performed on microarray gene expression data since it groups genes which have similar expression patterns and enables the explorati...
Xuejun Liu, Kevin K. Lin, Bogi Andersen, Magnus Ra...
95
Voted
BMCBI
2006
118views more  BMCBI 2006»
15 years 26 days ago
Microarray image analysis: background estimation using quantile and morphological filters
Background: In a microarray experiment the difference in expression between genes on the same slide is up to 103 fold or more. At low expression, even a small error in the estimat...
Anders Bengtsson, Henrik Bengtsson
BMCBI
2006
103views more  BMCBI 2006»
15 years 26 days ago
Probe-level linear model fitting and mixture modeling results in high accuracy detection of differential gene expression
Background: The identification of differentially expressed genes (DEGs) from Affymetrix GeneChips arrays is currently done by first computing expression levels from the low-level ...
Sébastien Lemieux
COMCOM
2006
168views more  COMCOM 2006»
15 years 26 days ago
Relay node placement in large scale wireless sensor networks
Scalability and extended lifetime are two critical design goals of any large scale wireless sensor network. A two-tiered network model has been proposed recently for this purpose....
Jian Tang, Bin Hao, Arunabha Sen