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BMCBI
2004
120views more  BMCBI 2004»
14 years 11 months ago
An approach to large scale identification of non-obvious structural similarities between proteins
Background: A new sequence independent bioinformatics approach allowing genome-wide search for proteins with similar three dimensional structures has been developed. By utilizing ...
Artem Cherkasov, Steven J. M. Jones
BMCBI
2004
123views more  BMCBI 2004»
14 years 11 months ago
galaxieEST: addressing EST identity through automated phylogenetic analysis
Background: Research involving expressed sequence tags (ESTs) is intricately coupled to the existence of large, well-annotated sequence repositories. Comparatively complete and sa...
R. Henrik Nilsson, Balaji Rajashekar, Karl-Henrik ...
BMCBI
2008
155views more  BMCBI 2008»
14 years 12 months ago
ComPath: comparative enzyme analysis and annotation in pathway/subsystem contexts
Background: Once a new genome is sequenced, one of the important questions is to determine the presence and absence of biological pathways. Analysis of biological pathways in a ge...
Kwangmin Choi, Sun Kim
APIN
2000
120views more  APIN 2000»
14 years 11 months ago
Two-Loop Real-Coded Genetic Algorithms with Adaptive Control of Mutation Step Sizes
Genetic algorithms are adaptive methods based on natural evolution that may be used for search and optimization problems. They process a population of search space solutions with t...
Francisco Herrera, Manuel Lozano
93
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BMCBI
2007
162views more  BMCBI 2007»
14 years 12 months ago
Genome-wide identification of specific oligonucleotides using artificial neural network and computational genomic analysis
Background: Genome-wide identification of specific oligonucleotides (oligos) is a computationallyintensive task and is a requirement for designing microarray probes, primers, and ...
Chun-Chi Liu, Chin-Chung Lin, Ker-Chau Li, Wen-Shy...