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BMCBI
2010
181views more  BMCBI 2010»
14 years 10 months ago
Intensity dependent estimation of noise in microarrays improves detection of differentially expressed genes
Background: In many microarray experiments, analysis is severely hindered by a major difficulty: the small number of samples for which expression data has been measured. When one ...
Amit Zeisel, Amnon Amir, Wolfgang J. Köstler,...
BMCBI
2006
106views more  BMCBI 2006»
14 years 9 months ago
Gene and protein nomenclature in public databases
Background: Frequently, several alternative names are in use for biological objects such as genes and proteins. Applications like manual literature search, automated text-mining, ...
Katrin Fundel, Ralf Zimmer
BMCBI
2011
14 years 4 months ago
Multiclass classification of microarray data samples with a reduced number of genes
Background: Multiclass classification of microarray data samples with a reduced number of genes is a rich and challenging problem in Bioinformatics research. The problem gets hard...
Elizabeth Tapia, Leonardo Ornella, Pilar Bulacio, ...
BMCBI
2010
178views more  BMCBI 2010»
14 years 10 months ago
Selecting high-dimensional mixed graphical models using minimal AIC or BIC forests
Background: Chow and Liu showed that the maximum likelihood tree for multivariate discrete distributions may be found using a maximum weight spanning tree algorithm, for example K...
David Edwards, Gabriel C. G. de Abreu, Rodrigo Lab...
BMCBI
2005
133views more  BMCBI 2005»
14 years 9 months ago
Ab initio identification of putative human transcription factor binding sites by comparative genomics
Background: Understanding transcriptional regulation of gene expression is one of the greatest challenges of modern molecular biology. A central role in this mechanism is played b...
Davide Corà, Carl Herrmann, Christoph Diete...