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BMCBI
2010
123views more  BMCBI 2010»
15 years 6 months ago
A new protein binding pocket similarity measure based on comparison of clouds of atoms in 3D: application to ligand prediction
Background: Predicting which molecules can bind to a given binding site of a protein with known 3D structure is important to decipher the protein function, and useful in drug desi...
Brice Hoffmann, Mikhail Zaslavskiy, Jean-Philippe ...
BMCBI
2007
147views more  BMCBI 2007»
15 years 6 months ago
Improved residue contact prediction using support vector machines and a large feature set
Background: Predicting protein residue-residue contacts is an important 2D prediction task. It is useful for ab initio structure prediction and understanding protein folding. In s...
Jianlin Cheng, Pierre Baldi
EXPERT
2008
120views more  EXPERT 2008»
15 years 6 months ago
The CKC Challenge: Exploring Tools for Collaborative Knowledge Construction
The great success of Web 2.0 is mainly fuelled by an infrastructure that allows web users to create, share, tag, and connect content and knowledge easily. The tools for developing...
Natalya Fridman Noy, Abhita Chugh, Harith Alani
BMCBI
2005
100views more  BMCBI 2005»
15 years 6 months ago
EvDTree: structure-dependent substitution profiles based on decision tree classification of 3D environments
Background: Structure-dependent substitution matrices increase the accuracy of sequence alignments when the 3D structure of one sequence is known, and are successful e.g. in fold ...
Jean-Christophe Gelly, Laurent Chiche, Jér&...
CAD
2005
Springer
15 years 6 months ago
Computer-aided design of porous artifacts
Heterogeneous structures represent an important new frontier for 21st century engineering. Human tissues, composites, `smart' and multimaterial objects are all physically man...
Craig A. Schroeder, William C. Regli, Ali Shokoufa...