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BMCBI
2006
170views more  BMCBI 2006»
15 years 4 months ago
Biclustering of gene expression data by non-smooth non-negative matrix factorization
Background: The extended use of microarray technologies has enabled the generation and accumulation of gene expression datasets that contain expression levels of thousands of gene...
Pedro Carmona-Saez, Roberto D. Pascual-Marqui, Fra...
BMCBI
2006
117views more  BMCBI 2006»
15 years 4 months ago
Incorporating background frequency improves entropy-based residue conservation measures
Background: Several entropy-based methods have been developed for scoring sequence conservation in protein multiple sequence alignments. High scoring amino acid positions may corr...
Kai Wang, Ram Samudrala
BMCBI
2006
94views more  BMCBI 2006»
15 years 4 months ago
Genepi: a blackboard framework for genome annotation
Background: Genome annotation can be viewed as an incremental, cooperative, data-driven, knowledge-based process that involves multiple methods to predict gene locations and struc...
Stéphane Descorps-Declère, Danielle ...
BMCBI
2007
95views more  BMCBI 2007»
15 years 4 months ago
Methods for estimating human endogenous retrovirus activities from EST databases
Background: Human endogenous retroviruses (HERVs) are surviving traces of ancient retrovirus infections and now reside within the human DNA. Recently HERV expression has been dete...
Merja Oja, Jaakko Peltonen, Jonas Blomberg, Samuel...
JPDC
2008
134views more  JPDC 2008»
15 years 4 months ago
Middleware for data mining applications on clusters and grids
This paper gives an overview of two middleware systems that have been developed over the last 6 years to address the challenges involved in developing parallel and distributed imp...
Leonid Glimcher, Ruoming Jin, Gagan Agrawal