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NAR
2006
108views more  NAR 2006»
15 years 3 months ago
GLIDA: GPCR-ligand database for chemical genomic drug discovery
G-protein coupled receptors (GPCRs) represent one of the most important families of drug targets in pharmaceutical development. GPCR-LIgand DAtabase (GLIDA) is a novel public GPCR...
Yasushi Okuno, Jiyoon Yang, Kei Taneishi, Hiroaki ...
PPL
2008
101views more  PPL 2008»
15 years 3 months ago
Skeletal Parallel Programming with OCamlP3l 2.0
Parallel programming has proven to be an effective technique to improve the performance of computationally intensive applications. However, writing parallel programs is not easy, ...
Roberto Di Cosmo, Zheng Li, Susanna Pelagatti, Pie...
PR
2006
116views more  PR 2006»
15 years 3 months ago
Shared farthest neighbor approach to clustering of high dimensionality, low cardinality data
Clustering algorithms are routinely used in biomedical disciplines, and are a basic tool in bioinformatics. Depending on the task at hand, there are two most popular options, the ...
Stefano Rovetta, Francesco Masulli
SIAMSC
2008
191views more  SIAMSC 2008»
15 years 3 months ago
ORBIT: Optimization by Radial Basis Function Interpolation in Trust-Regions
Abstract. We present a new derivative-free algorithm, ORBIT, for unconstrained local optimization of computationally expensive functions. A trust-region framework using interpolati...
Stefan M. Wild, Rommel G. Regis, Christine A. Shoe...
RE
2006
Springer
15 years 3 months ago
The Detection and Classification of Non-Functional Requirements with Application to Early Aspects
This paper introduces an information retrieval based approach for automating the detection and classification of non-functional requirements (NFRs). Early detection of NFRs is use...
Jane Cleland-Huang, Raffaella Settimi, Xuchang Zou...