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BMCBI
2004
126views more  BMCBI 2004»
14 years 9 months ago
Visualization and analysis of microarray and gene ontology data with treemaps
Background: The increasing complexity of genomic data presents several challenges for biologists. Limited computer monitor views of data complexity and the dynamic nature of data ...
Eric H. Baehrecke, Niem Dang, Ketan Babaria, Ben S...
BMCBI
2004
158views more  BMCBI 2004»
14 years 9 months ago
Improvement of alignment accuracy utilizing sequentially conserved motifs
Background: Multiple sequence alignment algorithms are very important tools in molecular biology today. Accurate alignment of proteins is central to several areas such as homology...
Saikat Chakrabarti, Nitin Bhardwaj, Prem A. Anand,...
BMCBI
2004
96views more  BMCBI 2004»
14 years 9 months ago
A hybrid clustering approach to recognition of protein families in 114 microbial genomes
Background: Grouping proteins into sequence-based clusters is a fundamental step in many bioinformatic analyses (e.g., homology-based prediction of structure or function). Standar...
Timothy J. Harlow, J. Peter Gogarten, Mark A. Raga...
BMCBI
2004
106views more  BMCBI 2004»
14 years 9 months ago
ESTIMA, a tool for EST management in a multi-project environment
Background: Single-pass, partial sequencing of complementary DNA (cDNA) libraries generates thousands of chromatograms that are processed into high quality expressed sequence tags...
Charu G. Kumar, Richard LeDuc, George Gong, Levan ...
BMCBI
2004
96views more  BMCBI 2004»
14 years 9 months ago
Identification of regions in multiple sequence alignments thermodynamically suitable for targeting by consensus oligonucleotides
Background: Computer programs for the generation of multiple sequence alignments such as "Clustal W" allow detection of regions that are most conserved among many sequen...
Olga V. Matveeva, Brian T. Foley, Vladimir A. Nemt...