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BMCBI
2010
160views more  BMCBI 2010»
15 years 6 months ago
Extracting consistent knowledge from highly inconsistent cancer gene data sources
Background: Hundreds of genes that are causally implicated in oncogenesis have been found and collected in various databases. For efficient application of these abundant but diver...
Xue Gong, Ruihong Wu, Yuannv Zhang, Wenyuan Zhao, ...
BMCBI
2007
132views more  BMCBI 2007»
15 years 6 months ago
TPRpred: a tool for prediction of TPR-, PPR- and SEL1-like repeats from protein sequences
Background: Solenoid repeat proteins of the Tetratrico Peptide Repeat (TPR) family are involved as scaffolds in a broad range of protein-protein interactions. Several resources ar...
Manjunatha R. Karpenahalli, Andrei N. Lupas, Johan...
BMCBI
2007
134views more  BMCBI 2007»
15 years 6 months ago
Automatic generation of 3D motifs for classification of protein binding sites
Background: Since many of the new protein structures delivered by high-throughput processes do not have any known function, there is a need for structure-based prediction of prote...
Jean-Christophe Nebel, Pawel Herzyk, David R. Gilb...
BMCBI
2007
181views more  BMCBI 2007»
15 years 6 months ago
ASMPKS: an analysis system for modular polyketide synthases
Background: Polyketides are secondary metabolites of microorganisms with diverse biological activities, including pharmacological functions such as antibiotic, antitumor and agroc...
Hongseok Tae, Eun-Bae Kong, Kiejung Park
BMCBI
2007
135views more  BMCBI 2007»
15 years 6 months ago
Detecting multivariate differentially expressed genes
Background: Gene expression is governed by complex networks, and differences in expression patterns between distinct biological conditions may therefore be complex and multivariat...
Roland Nilsson, José M. Peña, Johan ...
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