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BMCBI
2005
14 years 9 months ago
2005
Background: Sequence alignment is a common tool in bioinformatics and comparative genomics. It is generally assumed that multiple sequence alignment yields better results than pai...
BMCBI
2005
14 years 9 months ago
2005
Background: In a genetic interaction, the phenotype of a double mutant differs from the combined phenotypes of the underlying single mutants. When the single mutants have no growt...
BMCBI
2005
14 years 9 months ago
2005
Background: Clustering the ESTs from a large dataset representing a single species is a convenient starting point for a number of investigations into gene discovery, genome evolut...
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BMCBI
2005
14 years 9 months ago
2005
Background: Reconstructing regulatory networks from gene expression profiles is a challenging problem of functional genomics. In microarray studies the number of samples is often ...
BMCBI
2005
14 years 9 months ago
2005
Background: The identification of local similarities between two protein structures can provide clues of a common function. Many different methods exist for searching for similar ...