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105
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BMCBI
2006
15 years 18 days ago
2006
Background: In our previous studies, we found that the sites in prokaryotic genomes which are most susceptible to duplex destabilization under the negative superhelical stresses t...
106
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BMCBI
2006
15 years 18 days ago
2006
Background: The functional annotation of proteins relies on published information concerning their close and remote homologues in sequence databases. Evidence for remote sequence ...
127
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BMCBI
2006
15 years 18 days ago
2006
Background: A transcriptional regulatory module (TRM) is a set of genes that is regulated by a common set of transcription factors (TFs). By organizing the genome into TRMs, a liv...
95
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BMCBI
2007
15 years 17 days ago
2007
Background: ChIP-chip data, which indicate binding of transcription factors (TFs) to DNA regions in vivo, are widely used to reconstruct transcriptional regulatory networks. Howev...
107
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BMCBI
2007
15 years 17 days ago
2007
Background: The web has seen an explosion of chemistry and biology related resources in the last 15 years: thousands of scientific journals, databases, wikis, blogs and resources ...