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BMCBI
2005
122views more  BMCBI 2005»
15 years 1 months ago
Quantitative analysis of EGR proteins binding to DNA: assessing additivity in both the binding site and the protein
Background: Recognition codes for protein-DNA interactions typically assume that the interacting positions contribute additively to the binding energy. While this is known to not ...
Jiajian Liu, Gary D. Stormo
BMCBI
2005
116views more  BMCBI 2005»
15 years 1 months ago
Can Zipf's law be adapted to normalize microarrays?
Background: Normalization is the process of removing non-biological sources of variation between array experiments. Recent investigations of data in gene expression databases for ...
Timothy Lu, Christine M. Costello, Peter J. P. Cro...
JCB
2007
130views more  JCB 2007»
15 years 1 months ago
Bayesian Inference of MicroRNA Targets from Sequence and Expression Data
MicroRNAs (miRNAs) regulate a large proportion of mammalian genes by hybridizing to targeted messenger RNAs (mRNAs) and down-regulating their translation into protein. Although mu...
Jim C. Huang, Quaid Morris, Brendan J. Frey
TOSEM
2008
168views more  TOSEM 2008»
15 years 1 months ago
Developing and debugging algebraic specifications for Java classes
Modern programs make extensive use of reusable software libraries. For example, a study of a number of large Java applications shows that between 17% and 30% of the classes in tho...
Johannes Henkel, Christoph Reichenbach, Amer Diwan
ASE
2004
108views more  ASE 2004»
15 years 1 months ago
CODEWEAVE: Exploring Fine-Grained Mobility of Code
er is concerned with an abstract exploration of code mobility constructs designed for use in settings where the level of granularity associated with the mobile units exhibits sign...
Cecilia Mascolo, Gian Pietro Picco, Gruia-Catalin ...
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