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» Human Genome Annotation
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126
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BMCBI
2007
183views more  BMCBI 2007»
15 years 3 months ago
Considerations in the identification of functional RNA structural elements in genomic alignments
Background: Accurate identification of novel, functional noncoding (nc) RNA features in genome sequence has proven more difficult than for exons. Current algorithms identify and s...
Tomas Babak, Benjamin J. Blencowe, Timothy R. Hugh...
136
Voted
BMCBI
2006
92views more  BMCBI 2006»
15 years 3 months ago
A jumping profile Hidden Markov Model and applications to recombination sites in HIV and HCV genomes
Background: Jumping alignments have recently been proposed as a strategy to search a given multiple sequence alignment A against a database. Instead of comparing a database sequen...
Anne-Kathrin Schultz, Ming Zhang, Thomas Leitner, ...
130
Voted
CCS
2009
ACM
15 years 10 months ago
Learning your identity and disease from research papers: information leaks in genome wide association study
Genome-wide association studies (GWAS) aim at discovering the association between genetic variations, particularly single-nucleotide polymorphism (SNP), and common diseases, which...
Rui Wang, Yong Fuga Li, XiaoFeng Wang, Haixu Tang,...
BMCBI
2011
14 years 7 months ago
Cell Subset Prediction for Blood Genomic Studies
Background: Genome-wide transcriptional profiling of patient blood samples offers a powerful tool to investigate underlying disease mechanisms and personalized treatment decisions...
Christopher R. Bolen, Mohamed Uduman, Steven H. Kl...
149
Voted
BMCBI
2008
140views more  BMCBI 2008»
15 years 3 months ago
FUNYBASE: a FUNgal phYlogenomic dataBASE
Background: The increasing availability of fungal genome sequences provides large numbers of proteins for evolutionary and phylogenetic analyses. However the heterogeneity of data...
Sylvain Marthey, Gabriela Aguileta, Françoi...