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155
Voted
BMCBI
2006
15 years 3 months ago
2006
Background: Single nucleotide polymorphisms (SNPs) are locations at which the genomic sequences of population members differ. Since these differences are known to follow patterns,...
150
Voted
BMCBI
2006
15 years 3 months ago
2006
Background: Massive gene expression changes in different cellular states measured by microarrays, in fact, reflect just an "echo" of real molecular processes in the cell...
130
Voted
BMCBI
2006
15 years 3 months ago
2006
Background: ESTs are a tremendous resource for determining the exon-intron structures of genes, but even extensive EST sequencing tends to leave many exons and genes untouched. Ge...
131
Voted
BMCBI
2006
15 years 3 months ago
2006
Background: Analysis of genomes evolving via block-interchange events leads to a combinatorial problem of sorting by block-interchanges, which has been studied recently to evaluat...
143
Voted
BMCBI
2006
15 years 3 months ago
2006
Background: Common fragile sites (cfs) are specific regions in the human genome that are particularly prone to genomic instability under conditions of replicative stress. Several ...