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BMCBI
2006
138views more  BMCBI 2006»
14 years 9 months ago
Approximation properties of haplotype tagging
Background: Single nucleotide polymorphisms (SNPs) are locations at which the genomic sequences of population members differ. Since these differences are known to follow patterns,...
Staal A. Vinterbo, Stephan Dreiseitl, Lucila Ohno-...
BMCBI
2006
169views more  BMCBI 2006»
14 years 9 months ago
Beyond microarrays: Finding key transcription factors controlling signal transduction pathways
Background: Massive gene expression changes in different cellular states measured by microarrays, in fact, reflect just an "echo" of real molecular processes in the cell...
Alexander E. Kel, Nico Voss, Ruy Jauregui, Olga V....
BMCBI
2006
111views more  BMCBI 2006»
14 years 9 months ago
Using ESTs to improve the accuracy of de novo gene prediction
Background: ESTs are a tremendous resource for determining the exon-intron structures of genes, but even extensive EST sequencing tends to leave many exons and genes untouched. Ge...
Chaochun Wei, Michael R. Brent
BMCBI
2006
192views more  BMCBI 2006»
14 years 9 months ago
Analysis of circular genome rearrangement by fusions, fissions and block-interchanges
Background: Analysis of genomes evolving via block-interchange events leads to a combinatorial problem of sorting by block-interchanges, which has been studied recently to evaluat...
Chin Lung Lu, Yen-Lin Huang, Tsui Ching Wang, Hsie...
BMCBI
2006
142views more  BMCBI 2006»
14 years 9 months ago
Correlated fragile site expression allows the identification of candidate fragile genes involved in immunity and associated with
Background: Common fragile sites (cfs) are specific regions in the human genome that are particularly prone to genomic instability under conditions of replicative stress. Several ...
Angela Re, Davide Corà, Alda Maria Puliti, ...
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