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110
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BMCBI
2007
15 years 2 months ago
2007
Background: Accurate identification of novel, functional noncoding (nc) RNA features in genome sequence has proven more difficult than for exons. Current algorithms identify and s...
116
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BMCBI
2008
15 years 2 months ago
2008
Background: Previous studies comparing quantitative proteomics and microarray data have generally found poor correspondence between the two. We hypothesised that this might in par...
126
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BMCBI
2007
15 years 2 months ago
2007
Background: Unsupervised annotation of proteins by software pipelines suffers from very high error rates. Spurious functional assignments are usually caused by unwarranted homolog...
118
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BMCBI
2008
15 years 2 months ago
2008
Background: Genome survey sequences (GSS) offer a preliminary global view of a genome since, unlike ESTs, they cover coding as well as non-coding DNA and include repetitive region...
110
Voted
BMCBI
2008
15 years 2 months ago
2008
Background: Ultraconserved elements are nucleotide or protein sequences with 100% identity (no mismatches, insertions, or deletions) in the same organism or between two or more or...