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BMCBI
2010
102views more  BMCBI 2010»
14 years 9 months ago
Quantized correlation coefficient for measuring reproducibility of ChIP-chip data
Background: Chromatin immunoprecipitation followed by microarray hybridization (ChIP-chip) is used to study protein-DNA interactions and histone modifications on a genome-scale. T...
Shouyong Peng, Mitzi I. Kuroda, Peter J. Park
BMCBI
2007
127views more  BMCBI 2007»
14 years 9 months ago
Characterization of protein-interaction networks in tumors
Background: Analyzing differential-gene-expression data in the context of protein-interaction networks (PINs) yields information on the functional cellular status. PINs can be for...
Alexander Platzer, Paul Perco, Arno Lukas, Bernd M...
BMCBI
2007
130views more  BMCBI 2007»
14 years 9 months ago
Exploiting residue-level and profile-level interface propensities for usage in binding sites prediction of proteins
Background: Recognition of binding sites in proteins is a direct computational approach to the characterization of proteins in terms of biological and biochemical function. Residu...
Qiwen Dong, Xiaolong Wang, Lei Lin, Yi Guan
BMCBI
2010
124views more  BMCBI 2010»
14 years 9 months ago
GPFrontend and GPGraphics: graphical analysis tools for genetic association studies
Background: Most software packages for whole genome association studies are non-graphical, purely text based programs originally designed to run with UNIX-like operating systems. ...
Steffen Uebe, Francesca Pasutto, Mandy Krumbiegel,...
BMCBI
2008
155views more  BMCBI 2008»
14 years 9 months ago
ComPath: comparative enzyme analysis and annotation in pathway/subsystem contexts
Background: Once a new genome is sequenced, one of the important questions is to determine the presence and absence of biological pathways. Analysis of biological pathways in a ge...
Kwangmin Choi, Sun Kim
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