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BMCBI
2007
127views more  BMCBI 2007»
14 years 10 months ago
Characterization of protein-interaction networks in tumors
Background: Analyzing differential-gene-expression data in the context of protein-interaction networks (PINs) yields information on the functional cellular status. PINs can be for...
Alexander Platzer, Paul Perco, Arno Lukas, Bernd M...
BMCBI
2008
195views more  BMCBI 2008»
14 years 10 months ago
Goldsurfer2 (Gs2): A comprehensive tool for the analysis and visualization of genome wide association studies
Background: Genome wide association (GWA) studies are now being widely undertaken aiming to find the link between genetic variations and common diseases. Ideally, a well-powered G...
Fredrik Pettersson, Andrew P. Morris, Michael R. B...
BMCBI
2007
153views more  BMCBI 2007»
14 years 10 months ago
An exploration of alternative visualisations of the basic helix-loop-helix protein interaction network
Background: Alternative representations of biochemical networks emphasise different aspects of the data and contribute to the understanding of complex biological systems. In this ...
Brian J. Holden, John W. Pinney, Simon C. Lovell, ...
BMCBI
2008
179views more  BMCBI 2008»
14 years 10 months ago
Building pathway clusters from Random Forests classification using class votes
Background: Recent years have seen the development of various pathway-based methods for the analysis of microarray gene expression data. These approaches have the potential to bri...
Herbert Pang, Hongyu Zhao
BMCBI
2008
136views more  BMCBI 2008»
14 years 10 months ago
GPAT: Retrieval of genomic annotation from large genomic position datasets
Background: Recent genome wide transcription factor binding site or chromatin modification mapping analysis techniques, such as chromatin immunoprecipitation (ChIP) linked to DNA ...
Arnaud Krebs, Mattia Frontini, Làszlò...