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BMCBI
2008
142views more  BMCBI 2008»
14 years 10 months ago
Microarray data mining: A novel optimization-based approach to uncover biologically coherent structures
Background: DNA microarray technology allows for the measurement of genome-wide expression patterns. Within the resultant mass of data lies the problem of analyzing and presenting...
Meng Piao Tan, Erin N. Smith, James R. Broach, Chr...
BMCBI
2008
172views more  BMCBI 2008»
14 years 10 months ago
Compo: composite motif discovery using discrete models
Background: Computational discovery of motifs in biomolecular sequences is an established field, with applications both in the discovery of functional sites in proteins and regula...
Geir Kjetil Sandve, Osman Abul, Finn Drablø...
BMCBI
2006
137views more  BMCBI 2006»
14 years 10 months ago
A classification-based framework for predicting and analyzing gene regulatory response
Background: We have recently introduced a predictive framework for studying gene transcriptional regulation in simpler organisms using a novel supervised learning algorithm called...
Anshul Kundaje, Manuel Middendorf, Mihir Shah, Chr...
BMCBI
2006
182views more  BMCBI 2006»
14 years 10 months ago
AceTree: a tool for visual analysis of Caenorhabditis elegans embryogenesis
Background: The invariant lineage of the nematode Caenorhabditis elegans has potential as a powerful tool for the description of mutant phenotypes and gene expression patterns. We...
Thomas J. Boyle, Zhirong Bao, John I. Murray, Carl...
BMCBI
2006
150views more  BMCBI 2006»
14 years 10 months ago
CGAT: a comparative genome analysis tool for visualizing alignments in the analysis of complex evolutionary changes between clos
Background: The recent accumulation of closely related genomic sequences provides a valuable resource for the elucidation of the evolutionary histories of various organisms. Howev...
Ikuo Uchiyama, Toshio Higuchi, Ichizo Kobayashi