1847 search results - page 355 / 370 » Hybrid Functional Interpretations |
BMCBI
2010
14 years 10 months ago
2010
Background: Large genomes contain families of highly similar genes that cannot be individually identified by microarray probes. This limitation is due to thermodynamic restriction...
BMCBI
2010
14 years 10 months ago
2010
Emerging knowledge of whole prokaryotic transcriptomes could validate a number of theoretical concepts introduced in the early days of genomics. What are the rules connecting gene...
BMCBI
2010
14 years 10 months ago
2010
Background: Genome-scale metabolic reconstructions under the Constraint Based Reconstruction and Analysis (COBRA) framework are valuable tools for analyzing the metabolic capabili...
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BMCBI
2010
14 years 10 months ago
2010
Background: Protein-protein interaction (PPI) plays essential roles in cellular functions. The cost, time and other limitations associated with the current experimental methods ha...
BMCBI
2008
14 years 10 months ago
2008
Background: The availability of complete genomic sequences for hundreds of organisms promises to make obtaining genome-wide estimates of substitution rates, selective constraints ...