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BMCBI
2008
143views more  BMCBI 2008»
14 years 10 months ago
Automatic detection of exonic splicing enhancers (ESEs) using SVMs
Background: Exonic splicing enhancers (ESEs) activate nearby splice sites and promote the inclusion (vs. exclusion) of exons in which they reside, while being a binding site for S...
Britta Mersch, Alexander Gepperth, Sándor S...
BMCBI
2008
150views more  BMCBI 2008»
14 years 10 months ago
MOSAIC: an online database dedicated to the comparative genomics of bacterial strains at the intra-species level
Background: The recent availability of complete sequences for numerous closely related bacterial genomes opens up new challenges in comparative genomics. Several methods have been...
Hélène Chiapello, Annie Gendrault, C...
BMCBI
2008
110views more  BMCBI 2008»
14 years 10 months ago
Testing for treatment effects on gene ontology
In studies that use DNA arrays to assess changes in gene expression, it is preferable to measure the significance of treatment effects on a group of genes from a pathway or functi...
Taewon Lee, Varsha G. Desai, Cruz Velasco, Robert ...
BMCBI
2008
122views more  BMCBI 2008»
14 years 10 months ago
Reconstructing networks of pathways via significance analysis of their intersections
Background: Significance analysis at single gene level may suffer from the limited number of samples and experimental noise that can severely limit the power of the chosen statist...
Mirko Francesconi, Daniel Remondini, Nicola Nerett...
BMCBI
2008
126views more  BMCBI 2008»
14 years 10 months ago
ISOL@: an Italian SOLAnaceae genomics resource
Background: Present-day `-omics' technologies produce overwhelming amounts of data which include genome sequences, information on gene expression (transcripts and proteins) a...
Maria Luisa Chiusano, Nunzio D'Agostino, Alessandr...