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BMCBI
2006
2006
Searching for interpretable rules for disease mutations: a simulated annealing bump hunting strategy
14 years 10 months ago
Background: Understanding how amino acid substitutions affect protein functions is critical for the study of proteins and their implications in diseases. Although methods have bee...
BMCBI
2006
14 years 10 months ago
2006
Background: The use of exogenous small interfering RNAs (siRNAs) for gene silencing has quickly become a widespread molecular tool providing a powerful means for gene functional s...
GPEM
2000
14 years 9 months ago
2000
Genetic programming, in conjunction with advanced analytical instruments, is a novel tool for the investigation of complex biological systems at the whole-tissue level. In this stu...
AEI
2002
14 years 10 months ago
2002
Functionality of artifacts as well as structure and behavior plays crucial roles in problem-solving such as design. This article discusses automatic identifications of functional s...
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BMCBI
2007
14 years 10 months ago
2007
Background: The functions of human cells are carried out by biomolecular networks, which include proteins, genes, and regulatory sites within DNA that encode and control protein e...