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» I-TASSER server for protein 3D structure prediction
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BMCBI
2007
128views more  BMCBI 2007»
14 years 10 months ago
A robust and efficient algorithm for the shape description of protein structures and its application in predicting ligand bindin
Background: An accurate description of protein shape derived from protein structure is necessary to establish an understanding of protein-ligand interactions, which in turn will l...
Lei Xie, Philip E. Bourne
NAR
2006
82views more  NAR 2006»
14 years 10 months ago
PROFtmb: a web server for predicting bacterial transmembrane beta barrel proteins
PROFtmb predicts transmembrane beta-barrel (TMB) proteins in Gram-negative bacteria. For each query protein, PROFtmb provides both a Z-value indicating that the protein actually c...
Henry R. Bigelow, Burkhard Rost
BMCBI
2006
101views more  BMCBI 2006»
14 years 10 months ago
Predicting residue contacts using pragmatic correlated mutations method: reducing the false positives
Background: Predicting residues' contacts using primary amino acid sequence alone is an important task that can guide 3D structure modeling and can verify the quality of the ...
Petras J. Kundrotas, Emil Alexov
BMCBI
2008
128views more  BMCBI 2008»
14 years 10 months ago
Pairwise covariance adds little to secondary structure prediction but improves the prediction of non-canonical local structure
Background: Amino acid sequence probability distributions, or profiles, have been used successfully to predict secondary structure and local structure in proteins. Profile models ...
Christopher Bystroff, Bobbie-Jo M. Webb-Robertson
GECCO
2008
Springer
164views Optimization» more  GECCO 2008»
14 years 11 months ago
Genetic algorithms with local search optimization for protein structure prediction problem
This paper presents a new Genetic Algorithm for Protein Structure Prediction problem in both 2D and 3D hydrophobichydrophilic lattice models, introduced in [1]. Our algorithm evol...
Igor Berenboym, Mireille Avigal