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» IT Predictions for 2008
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127
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BMCBI
2008
178views more  BMCBI 2008»
15 years 26 days ago
A discriminative method for protein remote homology detection and fold recognition combining Top-n-grams and latent semantic ana
Background: Protein remote homology detection and fold recognition are central problems in bioinformatics. Currently, discriminative methods based on support vector machine (SVM) ...
Bin Liu, Xiaolong Wang, Lei Lin, Qiwen Dong, Xuan ...
BMCBI
2008
142views more  BMCBI 2008»
15 years 26 days ago
Strategies for measuring evolutionary conservation of RNA secondary structures
Background: Evolutionary conservation of RNA secondary structure is a typical feature of many functional non-coding RNAs. Since almost all of the available methods used for predic...
Andreas R. Gruber, Stephan H. F. Bernhart, Ivo L. ...
92
Voted
BMCBI
2008
127views more  BMCBI 2008»
15 years 26 days ago
Human Pol II promoter recognition based on primary sequences and free energy of dinucleotides
Background: Promoter region plays an important role in determining where the transcription of a particular gene should be initiated. Computational prediction of eukaryotic Pol II ...
Jian-Yi Yang, Yu Zhou, Zu-Guo Yu, Vo Anh, Li-Qian ...
BMCBI
2008
97views more  BMCBI 2008»
15 years 26 days ago
SiteSeek: Post-translational modification analysis using adaptive locality-effective kernel methods and new profiles
Background: Post-translational modifications have a substantial influence on the structure and functions of protein. Post-translational phosphorylation is one of the most common m...
Paul D. Yoo, Yung Shwen Ho, Bing Bing Zhou, Albert...
BMCBI
2008
98views more  BMCBI 2008»
15 years 26 days ago
PredGPI: a GPI-anchor predictor
Background: Several eukaryotic proteins associated to the extracellular leaflet of the plasma membrane carry a Glycosylphosphatidylinositol (GPI) anchor, which is linked to the C-...
Andrea Pierleoni, Pier Luigi Martelli, Rita Casadi...