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BMCBI
2008
178views more  BMCBI 2008»
15 years 2 months ago
A discriminative method for protein remote homology detection and fold recognition combining Top-n-grams and latent semantic ana
Background: Protein remote homology detection and fold recognition are central problems in bioinformatics. Currently, discriminative methods based on support vector machine (SVM) ...
Bin Liu, Xiaolong Wang, Lei Lin, Qiwen Dong, Xuan ...
BMCBI
2007
109views more  BMCBI 2007»
15 years 2 months ago
Computational RNA secondary structure design: empirical complexity and improved methods
Background: We investigate the empirical complexity of the RNA secondary structure design problem, that is, the scaling of the typical difficulty of the design task for various cl...
Rosalía Aguirre-Hernández, Holger H....
BMCBI
2008
118views more  BMCBI 2008»
15 years 2 months ago
Virtual screening of GPCRs: An in silico chemogenomics approach
The G-protein coupled receptor (GPCR) superfamily is currently the largest class of therapeutic targets. In silico prediction of interactions between GPCRs and small molecules is ...
Laurent Jacob, Brice Hoffmann, Véronique St...
BMCBI
2008
158views more  BMCBI 2008»
15 years 2 months ago
Real value prediction of protein solvent accessibility using enhanced PSSM features
Background: Prediction of protein solvent accessibility, also called accessible surface area (ASA) prediction, is an important step for tertiary structure prediction directly from...
Darby Tien-Hao Chang, Hsuan-Yu Huang, Yu-Tang Syu,...
BMCBI
2008
153views more  BMCBI 2008»
15 years 2 months ago
Improved general regression network for protein domain boundary prediction
Background: Protein domains present some of the most useful information that can be used to understand protein structure and functions. Recent research on protein domain boundary ...
Paul D. Yoo, Abdur R. Sikder, Bing Bing Zhou, Albe...
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