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BMCBI
2010
124views more  BMCBI 2010»
14 years 9 months ago
Comparative analysis of acute and chronic corticosteroid pharmacogenomic effects in rat liver: Transcriptional dynamics and regu
Background: Comprehensively understanding corticosteroid pharmacogenomic effects is an essential step towards an insight into the underlying molecular mechanisms for both benefici...
Tung T. Nguyen, Richard R. Almon, Debra C. DuBois,...
SIGMOD
2002
ACM
132views Database» more  SIGMOD 2002»
15 years 10 months ago
Clustering by pattern similarity in large data sets
Clustering is the process of grouping a set of objects into classes of similar objects. Although definitions of similarity vary from one clustering model to another, in most of th...
Haixun Wang, Wei Wang 0010, Jiong Yang, Philip S. ...
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BMCBI
2010
130views more  BMCBI 2010»
14 years 9 months ago
A statistical approach to finding overlooked genetic associations
Background: Complexity and noise in expression quantitative trait loci (eQTL) studies make it difficult to distinguish potential regulatory relationships among the many interactio...
Andrew K. Rider, Geoffrey Siwo, Nitesh V. Chawla, ...
BMCBI
2005
122views more  BMCBI 2005»
14 years 9 months ago
A microarray data-based semi-kinetic method for predicting quantitative dynamics of genetic networks
Background: Elucidating the dynamic behaviour of genetic regulatory networks is one of the most significant challenges in systems biology. However, conventional quantitative predi...
Katsuyuki Yugi, Yoichi Nakayama, Shigen Kojima, To...
BMCBI
2006
240views more  BMCBI 2006»
14 years 9 months ago
Statistical analysis of real-time PCR data
Background: Even though real-time PCR has been broadly applied in biomedical sciences, data processing procedures for the analysis of quantitative real-time PCR are still lacking;...
Joshua S. Yuan, Ann Reed, Feng Chen, C. Neal Stewa...