This paper introduces GLOCSA as a new scoring function to rate multiple sequence alignments. It is intended to be simple, considering the whole alignment at once and reflecting t...
Background: The alignment of multiple protein sequences is a fundamental step in the analysis of biological data. It has traditionally been applied to analyzing protein families f...
Computationally identifying transcription factor binding sites in the promoter regions of genes is an important problem in computational biology and has been under intensive resea...
A genetic algorithm (GA) is utilised to discover known and novel PROSITE-like sequence templates that can be used to classify the sub-cellular location of eukaryotic proteins. Whi...
Background: Most profile and motif databases strive to classify protein sequences into a broad spectrum of protein families. The next step of such database studies should include ...