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GECCO
2008
Springer
165views Optimization» more  GECCO 2008»
13 years 7 months ago
Multiple sequence alignment using a GLOCSA guided genetic algorithm
This paper introduces GLOCSA as a new scoring function to rate multiple sequence alignments. It is intended to be simple, considering the whole alignment at once and reflecting t...
Edgar David Arenas-Díaz, Helga Ochoterena-B...
BMCBI
2005
132views more  BMCBI 2005»
13 years 6 months ago
Kalign - an accurate and fast multiple sequence alignment algorithm
Background: The alignment of multiple protein sequences is a fundamental step in the analysis of biological data. It has traditionally been applied to analyzing protein families f...
Timo Lassmann, Erik L. L. Sonnhammer
GECCO
2005
Springer
140views Optimization» more  GECCO 2005»
13 years 12 months ago
MDGA: motif discovery using a genetic algorithm
Computationally identifying transcription factor binding sites in the promoter regions of genes is an important problem in computational biology and has been under intensive resea...
Dongsheng Che, Yinglei Song, Khaled Rasheed
GECCO
2008
Springer
135views Optimization» more  GECCO 2008»
13 years 7 months ago
Evolving sequence patterns for prediction of sub-cellular locations of eukaryotic proteins
A genetic algorithm (GA) is utilised to discover known and novel PROSITE-like sequence templates that can be used to classify the sub-cellular location of eukaryotic proteins. Whi...
Greg Paperin
BMCBI
2002
133views more  BMCBI 2002»
13 years 6 months ago
Identification and characterization of subfamily-specific signatures in a large protein superfamily by a hidden Markov model app
Background: Most profile and motif databases strive to classify protein sequences into a broad spectrum of protein families. The next step of such database studies should include ...
Kevin Truong, Mitsuhiko Ikura