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108
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BMCBI
2006
86views more  BMCBI 2006»
15 years 3 months ago
The impact of sample imbalance on identifying differentially expressed genes
Background: Recently several statistical methods have been proposed to identify genes with differential expression between two conditions. However, very few studies consider the p...
Kun Yang, Jianzhong Li, Hong Gao
117
Voted
BMCBI
2006
102views more  BMCBI 2006»
15 years 3 months ago
MycoperonDB: a database of computationally identified operons and transcriptional units in Mycobacteria
Background: A key post genomics challenge is to identify how genes in an organism come together and perform physiological functions. An important first step in this direction is t...
Sarita Ranjan, Ranjit Kumar Gundu, Akash Ranjan
134
Voted
BMCBI
2006
127views more  BMCBI 2006»
15 years 3 months ago
A graph-search framework for associating gene identifiers with documents
Background: One step in the model organism database curation process is to find, for each article, the identifier of every gene discussed in the article. We consider a relaxation ...
William W. Cohen, Einat Minkov
BMCBI
2006
75views more  BMCBI 2006»
15 years 3 months ago
A machine learning strategy to identify candidate binding sites in human protein-coding sequence
Background: The splicing of RNA transcripts is thought to be partly promoted and regulated by sequences embedded within exons. Known sequences include binding sites for SR protein...
Thomas Down, Bernard Leong, Tim J. P. Hubbard
123
Voted
CN
2007
141views more  CN 2007»
15 years 3 months ago
Identifying lossy links in wired/wireless networks by exploiting sparse characteristics
In this paper, we consider the problem of estimating link loss rates based on end-to-end path loss rates in order to identify lossy links on the network. We first derive a maximu...
Hyuk Lim, Jennifer C. Hou