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BMCBI
2008
85views more  BMCBI 2008»
14 years 9 months ago
Wanted: unique names for unique atom positions. PDB-wide analysis of diastereotopic atom names of small molecules containing dip
Background: Biological chemistry is very stereospecific. Nonetheless, the diastereotopic oxygen atoms of diphosphate-containing molecules in the Protein Data Bank (PDB) are often ...
Christopher A. Bottoms, Dong Xu
NCA
2007
IEEE
14 years 9 months ago
A data reduction approach for resolving the imbalanced data issue in functional genomics
Learning from imbalanced data occurs frequently in many machine learning applications. One positive example to thousands of negative instances is common in scientific applications...
Kihoon Yoon, Stephen Kwek
87
Voted
NAR
2011
214views Computer Vision» more  NAR 2011»
14 years 11 days ago
starBase: a database for exploring microRNA-mRNA interaction maps from Argonaute CLIP-Seq and Degradome-Seq data
MicroRNAs (miRNAs) represent an important class of small non-coding RNAs (sRNAs) that regulate gene expression by targeting messenger RNAs. However, assigning miRNAs to their regu...
Jian-Hua Yang, Jun-Hao Li, Peng Shao, Hui Zhou, Yu...
KDD
2009
ACM
208views Data Mining» more  KDD 2009»
15 years 10 months ago
A principled and flexible framework for finding alternative clusterings
The aim of data mining is to find novel and actionable insights in data. However, most algorithms typically just find a single (possibly non-novel/actionable) interpretation of th...
Zijie Qi, Ian Davidson
AUSDM
2008
Springer
212views Data Mining» more  AUSDM 2008»
14 years 11 months ago
Clustering and Classification of Maintenance Logs using Text Data Mining
Spreadsheets applications allow data to be stored with low development overheads, but also with low data quality. Reporting on data from such sources is difficult using traditiona...
Brett Edwards, Michael Zatorsky, Richi Nayak