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BIOCOMP
2007
14 years 11 months ago
Biomarker Discovery Across Annotated and Unannotated Microarray Datasets Using Semi-Supervised Learning
The growing body of DNA microarray data has the potential to advance our understanding of the molecular basis of disease. However annotating microarray datasets with clinically us...
Cole Harris, Noushin Ghaffari
ICARIS
2004
Springer
15 years 3 months ago
Definition of MHC Supertypes Through Clustering of MHC Peptide Binding Repertoires
MHC molecules, also known in the human as human leukocyte antigens (HLA), display peptides on antigen presenting cell surfaces for subsequent T cell recognition. Identification of ...
Pedro A. Reche, Ellis L. Reinherz
BMCBI
2010
143views more  BMCBI 2010»
14 years 9 months ago
Shape based kinetic outlier detection in real-time PCR
Background: Real-time PCR has recently become the technique of choice for absolute and relative nucleic acid quantification. The gold standard quantification method in real-time P...
Davide Sisti, Michele Guescini, Marco B. L. Rocchi...
BMCBI
2004
120views more  BMCBI 2004»
14 years 9 months ago
An approach to large scale identification of non-obvious structural similarities between proteins
Background: A new sequence independent bioinformatics approach allowing genome-wide search for proteins with similar three dimensional structures has been developed. By utilizing ...
Artem Cherkasov, Steven J. M. Jones
92
Voted
BMCBI
2006
148views more  BMCBI 2006»
14 years 9 months ago
Exploiting the full power of temporal gene expression profiling through a new statistical test: Application to the analysis of m
Background: The identification of biologically interesting genes in a temporal expression profiling dataset is challenging and complicated by high levels of experimental noise. Mo...
Veronica Vinciotti, Xiaohui Liu, Rolf Turk, Emile ...