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RECOMB
2009
Springer
15 years 4 months ago
Inferring the Recent Duplication History of a Gene Cluster
Abstract. Much important evolutionary activity occurs in gene clusters, where a copy of a gene may be free to evolve new functions. Computational methods to extract evolutionary in...
Giltae Song, Louxin Zhang, Tomás Vinar, Web...
99
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BMCBI
2007
173views more  BMCBI 2007»
14 years 9 months ago
Recursive Cluster Elimination (RCE) for classification and feature selection from gene expression data
Background: Classification studies using gene expression datasets are usually based on small numbers of samples and tens of thousands of genes. The selection of those genes that a...
Malik Yousef, Segun Jung, Louise C. Showe, Michael...
ECAI
2004
Springer
15 years 1 months ago
Avoiding Data Overfitting in Scientific Discovery: Experiments in Functional Genomics
Functional genomics is a typical scientific discovery domain characterized by a very large number of attributes (genes) relative to the number of examples (observations). The dang...
Dragan Gamberger, Nada Lavrac
NAR
2000
85views more  NAR 2000»
14 years 9 months ago
MitoNuc and MitoAln: two related databases of nuclear genes coding for mitochondrial proteins
Mitochondria, besides their central role in energy metabolism, have recently been found to be involved in a number of basic processes of cell life and to contribute to the pathoge...
Graziano Pesole, Carmela Gissi, Domenico Catalano,...
BMCBI
2002
137views more  BMCBI 2002»
14 years 9 months ago
ORFer - retrieval of protein sequences and open reading frames from GenBank and storage into relational databases or text files
Background: Functional genomics involves the parallel experimentation with large sets of proteins. This requires management of large sets of open reading frames as a prerequisite ...
Konrad Büssow, Steve Hoffmann, Volker Sievert