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BIB
2010
140views more  BIB 2010»
14 years 7 months ago
Next generation sequencing in functional genomics
Genome-wide sequencing has enabled modern biomedical research to relate more and more events in healthy as well as disease-affected cells and tissues to the genomic sequence. Now ...
Thomas Werner
JCB
2006
129views more  JCB 2006»
14 years 9 months ago
GenRate: A Generative Model that Reveals Novel Transcripts in Genome-Tiling Microarray Data
Genome-wide microarray designs containing millions to hundreds of millions of probes are available for a variety of mammals, including mouse and human. These genome tiling arrays ...
Brendan J. Frey, Quaid Morris, Timothy R. Hughes
BMCBI
2010
155views more  BMCBI 2010»
14 years 7 months ago
BrEPS: a flexible and automatic protocol to compute enzyme-specific sequence profiles for functional annotation
Background: Models for the simulation of metabolic networks require the accurate prediction of enzyme function. Based on a genomic sequence, enzymatic functions of gene products a...
Constantin Bannert, A. Welfle, C. aus dem Spring, ...
BIOCOMP
2009
14 years 7 months ago
Gene Expression Analysis Using Communications, Coding and Information Theory Based Models
- Identification and annotation of all the functional elements in the genome, including genes and regulatory sequences, is a fundamental challenge in genomics and computational bio...
Mohammad Al Bataineh, Lun Huang, Ismaeel Muhamed, ...
ICDM
2005
IEEE
215views Data Mining» more  ICDM 2005»
15 years 3 months ago
CLUGO: A Clustering Algorithm for Automated Functional Annotations Based on Gene Ontology
We address the issue of providing highly informative and comprehensive annotations using information revealed by the structured vocabularies of Gene Ontology (GO). For a target, a...
In-Yee Lee, Jan-Ming Ho, Ming-Syan Chen