639 search results - page 82 / 128 » Identifying clusters of functionally related genes in genome... |
BIOINFORMATICS
2010
14 years 9 months ago
2010
Motivation: Tumorigenesis is an evolutionary process by which tumor cells acquire sequences of mutations leading to increased growth, invasiveness, and eventually metastasis. It i...
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BMCBI
2010
14 years 7 months ago
2010
Background: Despite experiments showing that the number of microRNA (miRNA) target sites is critical for miRNA targeting, most existing methods focus on identifying individual miR...
BMCBI
2002
14 years 9 months ago
2002
Background: An organism's ability to adapt to its particular environmental niche is of fundamental importance to its survival and proliferation. In the largest study of its k...
BMCBI
2010
14 years 9 months ago
2010
Background: A major goal of the analysis of high-dimensional RNA expression data from tumor tissue is to identify prognostic signatures for discriminating patient subgroups. For t...
BMCBI
2006
14 years 9 months ago
2006
Background: As numerous diseases involve errors in signal transduction, modern therapeutics often target proteins involved in cellular signaling. Interpretation of the activity of...