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BMCBI
2006
202views more  BMCBI 2006»
14 years 9 months ago
Integrated biclustering of heterogeneous genome-wide datasets for the inference of global regulatory networks
Background: The learning of global genetic regulatory networks from expression data is a severely under-constrained problem that is aided by reducing the dimensionality of the sea...
David J. Reiss, Nitin S. Baliga, Richard Bonneau
SDM
2007
SIAM
98views Data Mining» more  SDM 2007»
14 years 11 months ago
Lattice based Clustering of Temporal Gene-Expression Matrices
Individuals show different cell classes when they are in the different stages of a disease, have different disease subtypes, or have different response to a treatment or envir...
Yang Huang, Martin Farach-Colton
BMCBI
2010
130views more  BMCBI 2010»
14 years 9 months ago
Knowledge-guided gene ranking by coordinative component analysis
Background: In cancer, gene networks and pathways often exhibit dynamic behavior, particularly during the process of carcinogenesis. Thus, it is important to prioritize those gene...
Chen Wang, Jianhua Xuan, Huai Li, Yue Wang, Ming Z...
BIOINFORMATICS
2008
106views more  BIOINFORMATICS 2008»
14 years 9 months ago
Small RNA gene identification and mRNA target predictions in bacteria
Motivation: Bacterial small ribonucleic acids (sRNAs) that are not ribosomal and transfer or messenger RNAs were initially identified in the sixties whereas their molecular functi...
Christophe Pichon, Brice Felden
BMCBI
2010
97views more  BMCBI 2010»
14 years 4 months ago
A semi-parametric Bayesian model for unsupervised differential co-expression analysis
Background: Differential co-expression analysis is an emerging strategy for characterizing disease related dysregulation of gene expression regulatory networks. Given pre-defined ...
Johannes M. Freudenberg, Siva Sivaganesan, Michael...